Charaka Samhita, Vimanasthana 5.12
Yakrit pleeha cha moola Raktavaha Srotasam — The liver and spleen are the roots of the blood channels. Impairment produces skin conditions, jaundice, bleeding disorders, and spreading inflammatory conditions.

Classical documentation

Roots: Yakrit (liver) and Pleeha (spleen)

Primary Dosha: Pitta primarily — Ranjaka Pitta resides in the blood and liver; Rakta is the vehicle of Pitta

Classical conditions: Kushtha (skin conditions — excess Pitta-Rakta), Visarpa (spreading inflammations), Raktapitta (bleeding disorders from Pitta-vitiated blood), Gulma (abdominal masses from Rakta obstruction), Kamala (jaundice — impaired Ranjaka Pitta in Raktavaha Srotas)

How these channels are impaired

Excess pungent, sour, and hot foods; day-sleeping (increases Pitta and Kapha in blood channels); excessive anger (Krodha directly aggravates Pitta in Rakta); vigorous exercise in hot conditions; incompatible food combinations

Classical significance

Raktavaha Srotas maps to the vascular system and hepatic-splenic blood processing. The classical root in the liver and spleen precisely reflects modern haematology: the liver synthesises clotting factors and plasma proteins; the spleen filters aged red blood cells. The classical documentation of skin conditions as Raktavaha Srotas Dushti corresponds to modern dermatology's understanding of the liver-skin axis in inflammatory skin diseases.

Primary herbs for this Srotas
Manjistha (primary blood purifier), Kutki (liver/Ranjaka Pitta), Neem (Raktashoshana — blood detoxifier), Guduchi
The four types of Srotas impairment
Charaka Samhita documents four ways any Srotas can be impaired: Atipravritta (excessive flow — too much output); Sanga (obstruction — blockage stopping normal flow); Vimarga Gamana (flow in wrong direction — reflux, bleeding upward, etc.); Siragranthi (knotting/constriction — localised channel narrowing). These four apply to every Srotas — the specific disease produced depends on which channel is impaired and in which of these four ways.