Sushruta Samhita, Sharira 5.48
Shakhashu marmasthitih — In the limbs, the Marma are situated at the joints, vascular junctions, and neuromuscular convergences. Injury produces disability of that limb region. Therapeutically, these Marma are the most accessible and the most commonly used in Marma Abhyanga and external treatments.

Primary extremity Marma

Talahridaya ('heart of the sole/palm'): Located at the centre of the sole of the foot and the centre of the palm. Vaikalyakara. Governs the distribution of Prana to the entire limb. Therapeutically: the most important Marma for foot and hand reflexology practices. Classical Padabhyanga (foot massage) specifically targets Talahridaya as the primary Marma — documented in Dinacharya as beneficial for eye health, brain health, and sleep quality through the Prana channels ascending from the foot sole.

Kshipra: Between the first and second toes/fingers. Sadyah Pranahara — one of the few immediately fatal Marma in the extremities. Governs the primary Nadi (channel) ascending from the foot to the heart. Clinically: the Kshipra point corresponds to the LV-3 (Liver 3) acupuncture point — one of the most clinically validated acupuncture points in modern research, used for pain, anxiety, and hepatic conditions.

Kurcha: Thenar eminence (thumb muscle base) — hand; plantar pad — foot. Vaikalyakara. Governs the Mamsa (muscle) of the hand and foot.

Manibandha: Wrist joint. Vaikalyakara. Governs the entire hand. The pulse (Nadi) for Vata is assessed at the radial aspect of Manibandha.

Kurpara: Elbow joint. Vaikalyakara. Governs the forearm and hand channels.

Janu: Knee joint. Vaikalyakara. Governs the lower leg channels. The Janu Basti procedure (oil pooled on the knee) directly treats this Marma for knee joint conditions.

Ani: Lower thigh, just above the knee (bilateral on each limb — 4 total). Vaikalyakara. Governs blood supply to the lower leg.

Vitapa: Inguinal region — femoral triangle. Sadyah Pranahara. The femoral artery is the most dangerous extremity vascular location — the classical documentation precisely identifies the femoral triangle.

Marma Abhyanga — daily self-practice
The therapeutic application of Marma in daily practice: Charaka Samhita's Dinacharya chapter documents Abhyanga (oil massage) as protective of Marma — 'Sparsha abhyanga marmasanrakshana' — touch through Abhyanga protects the Marma. Daily self-massage with appropriate oil, paying specific attention to the joints (where most Vaikalyakara Marma are located), is the classical preventive application of Marma knowledge. This is accessible to everyone — unlike the clinical applications requiring trained practitioners.