Charaka Samhita, Sutrasthana 28 — Dhatu 3
Mamsa Dhatu: Karma — Lepana (coating/plastering the bones). Seat — Tendons and ligaments. Upadhatu — Ear canals. Mala — Ear wax, nasal crust, ear canal secretions — Kha-Mala (orifice waste).

Classical documentation

Mamsa Dhatu is muscle tissue — the tissue that provides structure, movement, and covering for the body. Charaka Samhita documents Mamsa as the primary Dhatu for Dharana (support and holding) of the body's form. Impaired Mamsa Dhatvagni produces both Mamsa Vriddhi (pathological growths — classical documentation of Granthi/cysts and Arbuda/tumour-type conditions) and Mamsa Kshaya (muscle wasting — the most visible form of tissue depletion).

Elements
Prithvi
Primary seat
Tendons and ligaments
Primary karma
Lepana (coating/plastering the bones)
Channel
Muscle channels — Mamsavaha Srotas
Upadhatu
Ear canals
Mala
Ear wax, nasal crust, ear canal secretions — Kha-Mala (orifice waste)

Signs of imbalance

Vriddhi (excess): Tumour-like swellings (Granthi), obesity in muscular form, stiffness, heaviness in limbs

Kshaya (deficiency): Muscle wasting, weakness, joint pain, emaciation, difficulty with movement

Dhatvagni — the tissue fire
Mamsa Dhatvagni — impaired in sedentary lifestyle and Vata-depleted states. When Dhatvagni is impaired — by Ama, improper diet, or Dosha aggravation — the tissue cannot properly form the next Dhatu in the chain. This is why classical treatment of tissue deficiency begins not with tissue-building herbs but with Deepana (kindling the Dhatvagni) and Pachana (digesting the Ama that impairs it).
Rasayana for this Dhatu
Bala, Ashwagandha, milk, meat soups (Mamsarasa) — Balya, Brimhana herbs. The classical Rasayana approach to Mamsa Dhatu: nourish the Dhatvagni first, then provide the specific Dhatu-building raw material through appropriate Rasayana preparations.
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