Charaka Samhita, Sutrasthana 28 — Dhatu 4
Meda Dhatu: Karma — Snehana (lubrication of body). Seat — Kidneys and omentum. Upadhatu — Sweat. Mala — Sweat (Sveda) — the primary mala of Meda Dhatu.

Classical documentation

Meda Dhatu is fat tissue — the lubricating, insulating, and energy-storing tissue. Charaka Samhita documents Meda as governing Snehana (lubrication) of the entire body — all joint movement, skin moistness, and channel patency depend on adequate Meda. The classical Medoroga (pathological fat accumulation) is the most thoroughly documented Dhatu excess condition — corresponding to what modern medicine classifies as metabolic syndrome and visceral obesity. Charaka Samhita's observation that excess Meda blocks Medovaha Srotas and impairs Meda Dhatvagni, creating a self-perpetuating accumulation cycle, precisely describes the modern understanding of adipose tissue dysfunction.

Elements
Prithvi + Jala
Primary seat
Kidneys and omentum
Primary karma
Snehana (lubrication of body)
Channel
Fat channels — Medovaha Srotas
Upadhatu
Sweat
Mala
Sweat (Sveda) — the primary mala of Meda Dhatu

Signs of imbalance

Vriddhi (excess): Obesity, difficulty in movement, excessive sweating, breathlessness on exertion, Prameha (metabolic conditions), Medoroga

Kshaya (deficiency): Dryness of joints (joint cracking), dry skin, hair loss, exhaustion

Dhatvagni — the tissue fire
Meda Dhatvagni — impaired most commonly in sedentary + excess sweet/oily food lifestyle. When Dhatvagni is impaired — by Ama, improper diet, or Dosha aggravation — the tissue cannot properly form the next Dhatu in the chain. This is why classical treatment of tissue deficiency begins not with tissue-building herbs but with Deepana (kindling the Dhatvagni) and Pachana (digesting the Ama that impairs it).
Rasayana for this Dhatu
Guggulu, Trikatu, Chitraka, Triphala — Lekhana (scraping), Medohara herbs. The classical Rasayana approach to Meda Dhatu: nourish the Dhatvagni first, then provide the specific Dhatu-building raw material through appropriate Rasayana preparations.
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